Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.
Acting
Hathaway's fierce fragility—she's doing Oscar-caliber work in a rom-com.
Cinematography
That golden-hour Pittsburgh glow makes illness look almost aspirational.
Writing
Surprisingly sharp on pharmaceutical sales—Zwick did his homework.
Director
Edward Zwick
Jake Gyllenhaal
Jamie Randall
Anne Hathaway
Maggie Murdock
Oliver Platt
Bruce Winston
Hank Azaria
Dr. Stan Knight
Josh Gad
Josh Randall
Gabriel Macht
Trey Hannigan
Judy Greer
Cindy
Jill Clayburgh
Nancy Randall
George Segal
Dr. James Randall
Kate Jennings Grant
Gina
Katheryn Winnick
"Lisa"
Kimberly Scott
Gail
Peter Friedman
California Man
Nikki DeLoach
Christy
Natalie Gold
Dr. Helen Randall
Trivia, insights & behind the scenes
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